Noodles Elaborated with Wheat and Bean Cotyledon Flours Improve Dyslipidemia and Liver Function in Streptozotocin-Induced Diabetic Rats.

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Tác giả: Raquel Karina Cruz-Bravo, Saul Fraire-Velazquez, Mayra Judith García-Robles, Mayra Denise Herrera, Jesús Adrián López, Luis Roberto Reveles-Torres, Claudia Araceli Reyes-Estrada, Megan Montserrat Torres-Aguilar

Ngôn ngữ: eng

Ký hiệu phân loại: 341.0267 Law of nations

Thông tin xuất bản: Netherlands : Plant foods for human nutrition (Dordrecht, Netherlands) , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 725722

 Type 2 diabetes (T2D) has been intrinsically linked to dyslipidemia. The intake of common beans (Phaseolus vulgaris) is recommended to lower the risk of developing this disease
  however, despite its beneficial contribution to health, its value chain has been weakened due to the lack of competitiveness in the market. The aim of this work was to evaluate the capacity of black bean cotyledon flour noodles to modulate lipid profile, atherosclerosis risk and hepatic enzymes levels using diabetic rats. T2D was induced with streptozotocin (30 mg/kg) after a five-week intake of a high fat diet. Metformin-, wheat noodles-, and bean noodles-treated groups were evaluated. During treatment, bean noodles lowered blood cholesterol. After sacrifice, its intake during four months also improved triglycerides and very low density lipoprotein, further related to in vitro inhibition of lipase activity. Moreover, bean noodles-fed rats exhibit decrease hepatic enzymes levels. Results suggest that intake of bean noodles prevent dyslipidemia and improve liver function. Based on the current results, further clinical trials are highly recommended to offer a novel functional food alternative to diabetic patients, and healthy-oriented human consumers.
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