Sudden changes are common in clinical trajectories. While theoretical work in complex dynamic systems has provided mathematical theories for various types and mechanisms of change, a concrete application for the field of psychopathology is still lacking. We aim to bridge this gap by outlining an applied theoretical framework using theoretical concepts of the natural sciences for the field of clinical psychopathology, also devoting attention to issues and providing recommendations that are specific to the psychopathology domain. First, the mechanisms and features of four distinct types of transitions are introduced: bifurcation-induced tipping (B-tipping), noise-induced tipping (N-tipping), rate-induced tipping (R-tipping), and noise-induced diffusion (N-diffusion). Those types of transitions differ in the main cause of the change and data characteristics. To illustrate their application to clinical phenomena, we present two real-life scenarios using simulated time series. These examples demonstrate how theoretical types of change may connect to clinical phenomena and highlight how different types of transitions can co-occur in various subsystems. In the first example, we show that the mood system and the momentary affect system of a patient with sudden loss may show B-tipping and N-diffusion at the same time
in the second example, we show that increasing the stimulus strengthening speed in exposure therapy may lead to R-tipping, while the therapeutic decision in this context may be caused by N-tipping. Finally, we lay out possible pathways for determining the appropriate type of transition for future empirical research, highlighting methods both from dynamic system research and special opportunities for research in clinical psychology. (PsycInfo Database Record (c) 2025 APA, all rights reserved).