Autonomous follicle quality control mechanisms: Innate immune signaling capabilities of granulosa cells.

• Tác giả: Francesca E Duncan, Jennifer L Gerton, Prianka H Hashim, Madeline J Perry, Michele T Pritchard
• Ngôn ngữ: eng
• Ký hiệu phân loại: 794.10285 Chess
• Thông tin xuất bản: England : Reproduction (Cambridge, England) , 2025
• Bộ sưu tập: NCBI
• ID: 726068

Tóm tắt

We synthesize current evidence that granulosa cells possess unique innate immune signaling capabilities. We suggest the novel concept that this serves as a quality control surveillance mechanism by integrating signals from the oocyte and ovarian microenvironment to prevent poor-quality follicles from producing gametes that contribute to the next generation.