Highly spatial-temporal electrochemical profiling of molecules trafficking at a single mitochondrion in one living cell.

• Tác giả: Desheng Chen, Dechen Jiang, Kang Liu, Rujia Liu, Yuanyuan Ma, Rongrong Pan, Lina Wu, Xiaobo Zhang
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Proceedings of the National Academy of Sciences of the United States of America , 2025
• Bộ sưu tập: NCBI
• ID: 726210

Tóm tắt

Simultaneous profiling of multiple molecules trafficking at a single organelle and the surrounding cytosol within a living cell is crucial for elucidating their functions, necessitating advanced techniques that provide high spatial-temporal resolution and molecule specificity. In this study, we present an electrochemical nanodevice based on a θ-nanopipette designed to coanalyze calcium ions (Ca