The contamination and persistence of Perfluorooctanoic Acid (PFOA) in aquatic environments have escalated environmental concerns, driving extensive research into effective decontamination strategies. To enhance the removal efficiency of PFOA via Advanced Reduction Processes (ARP) utilizing UV irradiation of tryptophan (Trp), carbon nanotubes (CNT) were incorporated, resulting in the development of a UV-Trp/CNT system. This novel process demonstrated a significant improvement in PFOA removal kinetics, as well as defluorination and Total Organic Carbon (TOC) reduction, and was effective across a broad spectrum of perfluoroalkyl carboxylic acids (PFCAs). In addition to the advanced reduction mechanism driven by hydrated electrons (e