Population ageing is rapid in China, so it is urgent to address this problem. Providing equitable, accessible, systematic and continuous health care services in life course and conducing life course study in elderly cohort can facilitate the construction of a life-course health care system for ageing. At present, there are limited prospective cohort studies of the elderly population in China, especially the oldest-old and centenarians, indicating that it is still necessary to establish and integrate cohorts of the elderly population to conduct epidemiological studies of the life course of the elderly. This special issue focuses on the topic of healthy ageing to discuss the future development of the health management of the elderly population in Beijing from different aspects and the potential risk factors affecting the health of the elderly, analyse the key influencing factors that can reduce all-cause and cardiovascular diseases mortalities, provide evidence support for the development of healthy ageing strategies, prevention of chronic diseases in the elderly and the construction of an ageing health care system in China.