Skull Oligometastasis From Cervical Cancer: A Case Report.

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Tác giả: Marwah Abdulkader, Husam S Almuhaish, Sultan Alsaiari, Safaa M Alshakankery, Mahmoud I Hadad, Tawfeeq A Tawfeeq

Ngôn ngữ: eng

Ký hiệu phân loại: 599.792 *Phoea

Thông tin xuất bản: United States : Cureus , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 728091

Bone metastasis is common, mostly resulting from hematogenous spread and usually carrying significant morbidity. The clinical presentation of bone metastasis depends on the site of metastasis and the involved structures. Radiological studies are usually able to detect the location and extent of the lesions with high accuracy. Management of bone metastasis is often a challenging mission. Here, we highlight the case of a 46-year-old postmenopausal lady who was diagnosed with cervical squamous cell carcinoma (SCC), human papillomavirus (HPV)-associated, and International Federation of Gynecology and Obstetrics (FIGO) stage IIIC1, after she presented with postcoital and irregular vaginal bleeding. The patient received chemoradiotherapy. Two months following treatment completion, she complained of painful occipital swelling. Computerized tomography (CT) of the brain revealed an occipital bone lytic lesion without intraparenchymal involvement, which was confirmed by magnetic resonance imaging (MRI). positron emission tomography-computed tomography (PET-CT) and nuclear bone scans excluded other sites of recurrences. She underwent surgical resection for this occipital lesion. The pathological analysis has confirmed the diagnosis of metastatic SCC of cervical origin. Given the poor prognosis of cervical cancer with bone metastasis, early diagnosis and proper palliative treatment probably preserve the quality of the patient's life despite the expected poor survival rate.
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