Epidemiological investigation of goose circovirus based on a newly developed indirect ELISA method.

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Jialong Chen, Jidang Chen, Rongchang Liu, Yi Tang, Chao Wang, He Wang, Wenchang Xue, Zhanxin Yao, Jipei Zhang, Wanjun Zhu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in veterinary science , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 728204

Goose circovirus (GoCV) is a recently identified pathogen in geese that is known to cause slow growth, feather disorder syndrome, and immunosuppression. Infection with GoCV may increase the risk of coinfections with multiple pathogens, leading to significant economic losses in the goose industry. However, due to a lack of serological detection methods, analysis of viral nucleic acids has been widely used in GoCV epidemiological surveys, which has limited accurate monitoring of the prevalence of GoCV. In this study, we developed and optimized an indirect ELISA method based on the prokaryotic-expressed recombinant GoCV capsid protein (△Cap-iELISA). The △Cap-iELISA was then used to test 349 goose serum samples collected from Guangdong, Shandong, and Fujian provinces during 2023 and 2024. The results showed that the positive rate of GoCV antibodies in the sampled geese was 71.06%. Further analysis indicated that the positive rate of GoCV antibodies increased with the age of the geese. In conclusion, we have developed a novel iELISA method that is well-suited for large-scale clinical detection and early diagnosis of GoCV infection. Notably, a significant correlation between age and the positive rate of GoCV antibodies among geese was observed based on this newly established method.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH