Design and synthesis of 3-(azepan-1-ylsulfonyl)-

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Tác giả: Mohammad A Khanfar, Mohammad Saleh

Ngôn ngữ: eng

Ký hiệu phân loại: 004.338 Systems analysis and design, computer architecture, performance evaluation of real-time computers

Thông tin xuất bản: Germany : Zeitschrift fur Naturforschung. C, Journal of biosciences , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 728325

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Carbonic anhydrase IX (CAIX) is known to be overexpressed in various tumors and plays a significant role in tumor development and progression. A series of 3-sulfonamide benzoate derivatives with a 7-membered azepane ring were synthesized and evaluated for their CAIX inhibitory activities. Most of the synthesized compounds successfully inhibited CAIX activities, exhibiting IC

1. Design
2. And
3. Synthesis

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