OBJECTIVE: This study aimed to assess patient satisfaction regarding facial appearance and quality of life pre- and post-reduction mandibuloplasty. In addition, it sought to investigate the factors influencing patient satisfaction. METHODS: Conducted as a prospective cohort study spanning from November 2020 to October 2023, participants were required to complete the FACE-Q assessment both before and one year following reduction mandibuloplasty. Normative FACE-Q values from individuals aged over 18 years were employed for comparison. A multivariate linear regression model was used to evaluate the impact of various factors on FACE-Q outcomes. RESULTS: Statistically significant enhancements in patient satisfaction were observed with overall appearance, lower face and jawline, and quality of life post-surgery. When compared to normative data, preoperative scores were significantly lower, yet postoperative scores reach levels comparable to those of the normative population. Moreover, patients generally perceived themselves as looking approximately 0.75 years younger post-surgery. Notably, patients aged 30 and younger experienced more pronounced improvements than those above 30. CONCLUSION: Reduction mandibuloplasty significantly contributes to the enhancement of facial appearance and quality of life, achieving results representative of the general population. Moreover, it positively influences the perception of apparent facial age. The extent of improvement varies among distinct age groups, emphasizing the recommendation for reduction mandibuloplasty at earlier ages, as older patients tended to exhibit less improvement. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .