Feasibility of Utilizing a Brief Neurocognitive Battery in 3-Year-Old Patients During Treatment for Acute Lymphoblastic Leukemia.

• Tác giả: Melanie Blair-Thies, Peter D Cole, Amy Fredrickson, Lisa Gennarini, Justine Kahn, Kara M Kelly, Bruno Michon, Sameera Ramjan, Stephen A Sands, Adrian Schembri, Lewis B Silverman, Thai-Hoa Tran, Jennifer J Greene Welch
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Pediatric blood & cancer , 2025
• Bộ sưu tập: NCBI
• ID: 729727

Tóm tắt

Treatment of acute lymphoblastic leukemia (ALL) is associated with neurocognitive deficits in young children. While computerized measures have been utilized in pediatric oncology research, they exclude patients below the age of 4 years. Patients enrolled on "Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents" were offered participation in an optional neurocognitive study. Three-year old patients did not differ from 4-year-old patients in their ability to perform or complete the tests. Including patients diagnosed at age 3 will serve to improve our understanding of at-risk patients and their neurocognitive trajectory both during and after treatment.