RATIONALE AND OBJECTIVES: Extrathyroidal extension (ETE) and BRAF MATERIALS AND METHODS: PubMed, Web of Science, Cochrane, and Embase databases were searched until May 7th, 2024. The Radiomics Quality Score tool assessed bias risk. Subgroup analyses based on radiomics and clinical characteristics were conducted. RESULTS: Our systematic review included 19 studies, encompassing 5337 PTC cases. Among these, 12 articles focused on ETE and seven articles focused on BRAF CONCLUSION: Radiomics in identifying ETE and BRAF