A leucine responsive small RNA AbcR200 regulates expression of the lactate utilization (lut) operon in Acinetobacter baumannii DS002.

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Tác giả: Sandhya Rani Behera, Ganeshwari Dhurve, Ashok Kumar Madikonda, Kashif Gulam Mohammad, Suresh Babu Pakala, Vijaykumar Pillalamarri, Dayananda Siddavattam, Prasad Tammineni, Harshita Nagasai Yakkala

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : The Journal of biological chemistry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 730337

Noncoding small RNAs are essential for modulating bacterial gene expression, especially under carbon and nutrient-limited conditions. In this study, by using both in silico and molecular hybridization tools, we identified a carbon source responsive small RNA in Acinetobacter baumannii DS002. Expression of corresponding gene, abcR200, located at the intergenic region of omt (O-methyl transferase) and orf72 genes, is under the transcriptional control of a global transcriptional factor, leucine responsive regulatory protein (Lrp). A sequence motif that serves as a target for Lrp was found overlapping the abcR200 promoter (P
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