Development of propranolol loaded SLN for transdermal delivery:

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Tác giả: Maryam Abedini Baghbadorani, Fatemeh Hajipour, Somayeh Handali, Mohammadamin Khazali, Behzad Sharif MakhmalZadeh, Eskandar Moghimipour, Fereshteh Nejaddehbashi, Somayeh Sohrabi, Ali Zangeneh

Ngôn ngữ: eng

Ký hiệu phân loại: 338.9 Economic development and growth

Thông tin xuất bản: England : Therapeutic delivery , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 730869

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AIM: The study aimed to formulate solid lipid nanoparticles (SLNs) for the transdermal delivery of PPL to improve skin retention and efficacy. MATERIALS AND METHOD: The particle size distribution of SLNs was determined and the morphology of SLNs was also analyzed by SEM. RESULTS: The results indicated successful encapsulation of PPL in SLNs (59.38%), which exhibited a spherical shape and smooth surface. Compared to PPL solution, SLNs demonstrated a prolonged drug release profile CONCLUSION: To the best of our knowledge, this is the first study that indicates SLNs can be considered as a promising nanocarriers for transdermal delivery of PPL.

1. Development
2. Of
3. Propranolol

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