OBJECTIVE: To assess the association of pediatric sleep disordered breathing (SDB) with control and severity of asthma, and to evaluate the comorbidities associated with both. METHODS: Based on the Sleep-Related Breathing Disorder scale, extracted from the Pediatric Sleep Questionnaire (SDBS-PSQ), children (5-15 years) with persistent asthma were classified as
with SDB (SDBS-PSQ≥0.33) and without SDB (SDBS-PSQ<
0.33), in a cross-sectional study. Baseline characteristics were compared. Control of asthma into well-controlled, not-well, and poorly controlled was assessed using childhood - asthma control test (c-ACT). Comorbidities like adeno-tonsillar hypertrophy, gastroesophageal reflux disease (GERD), obesity and allergic rhinitis (AR) for presence of SDB in asthma were assessed. RESULTS: Sixty asthmatics were included. Mild, moderate, and severe persistent asthma was observed in 26.67 %, 40 % and 33.33 % respectively, with 18.33 % asthmatics having SDB. 42.3 % of uncontrolled asthmatics had SDB. Baseline characteristics were similar in both groups. Asthmatics with SDB had higher frequency of severe persistent (63.6 % vs 26.5 %, p = 0.018) and uncontrolled asthma i.e. partly & poorly controlled (100 % vs 30.6 %, p <
0.002) versus asthmatics without SDB. Mean SDBS-PSQ score was higher in uncontrolled asthmatics compared to well-controlled asthmatics (0.255 ± 0.19 vs 0.047 ± 0.06, p <
0.002). Mean c-ACT score was lower with SDB (14.45 ± 3.20 vs 20.04 ± 4.56, p <
0.002), indicating poor control of asthma. A negative relationship was established between c-ACT and SDBS-PSQ (p <
0.002, r CONCLUSION: SDB may be associated with poor control and worsening severity of asthma. Concomitant AR was found in asthmatic children with SDB.