Multi-omics elucidates the kidney damage caused by aquatic Cu via the gut-kidney axis in ducks.

• Tác giả: Zhaoxia Cai, Li Chen, Mingcai Duan, Tiantian Gu, Jinyu Liu, Lizhi Lu, Yong Tian, Wenwu Xu, Tao Zeng
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Ecotoxicology and environmental safety , 2025
• Bộ sưu tập: NCBI
• ID: 731455

Tóm tắt

Copper (Cu) is an essential trace element for biological growth and development. Excessive intake of Cu exists harmful effects on organisms. However, whether excessive Cu intake induces kidney function damage by gut microbiota regulation remains unclear. Ducks are important species of waterfowl that are often exposed to Cu contamination in water sources. In this study, we aim to elucidate the effects of Cu exposure on renal inflammation through the gut-kidney axis in ducks. The ducks were gavaged with different doses of CuSO