XDH-1 inactivation causes xanthine stone formation in

• Tác giả: Ashley Van Asma, Sushila Bhattacharya, Chloe Brede, Robin R Fettig, Jennifer Snoozy, Kurt Warnhoff
• Ngôn ngữ: eng
• Ký hiệu phân loại: 294.5926 Hinduism
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 732475

Tóm tắt

Xanthine dehydrogenase (XDH-1) is a molybdenum cofactor (Moco) requiring enzyme that catabolizes hypoxanthine into xanthine and xanthine into uric acid, the final steps in purine catabolism. Human patients with mutations in