Nuclear Magnetic Resonance Screening Approach for Discovery of 5-Hydroxymethylfurfural Derivatives from Marine Fungus Fusarium oxysporum SP7.

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Tác giả: Kai-Lei Chen, Wen-Jian Lan, Hou-Jin Li, Yu-Peng Xuan, Yu-Hua Zhang, Ya-Jie Zhou

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Chemistry & biodiversity , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 732520

By tracing the characteristic proton and carbon nuclear magnetic resonance signals of the furan ring and aldehyde group, four novel 5-hydroxymethylfurfural derivatives, fusaroxysporins A-D (1-4), together with 10 known compounds were obtained from the marine fungus Fusarium oxysporum SP7. Their structures were elucidated by comprehensive spectroscopic analysis. The possible biogenic synthesis pathways of these compounds were speculated. Compound 1 showed moderate cytotoxic activity against the human type II alveolar epithelial cell A-549 and the human hepatocarcinoma cell line HepG2 with IC
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