Sex- and metabolic-specific association between cumulative body mass index and incident chronic kidney disease: A prospective community-based cohort study.

• Tác giả: Shuohua Chen, Lulu Chu, Yan He, Yuhao Li, Anxin Wang, Shouling Wu, Zhang Xia, Guozheng Xu, Yijun Zhang, Manqi Zheng, Yingting Zuo
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Nutrition, metabolism, and cardiovascular diseases : NMCD , 2025
• Bộ sưu tập: NCBI
• ID: 732640

Tóm tắt

 BACKGROUND AND AIM: Difference in metabolic status may cause inconsistent association between body mass index (BMI) and chronic kidney disease (CKD) in men and women. This study aimed to quantify sex-specific association between cumulative BMI (cumBMI) and incident CKD by different metabolic status. METHODS AND RESULTS: Participants free of CKD from the Kailuan Study were followed biennially from baseline (June 2006 to October 2007) to December 2019. cumBMI was calculated by use of follow-up BMI and follow-up time and was divided into low weight (<
 18.5 kg/m CONCLUSIONS: This study demonstrated sex- and metabolic-specific associations between BMI and CKD occurrence and advocates an individualized weight management strategy.