Multiple fingerprinting and cardioprotective activity of Salvia miltiorrhiza polysaccharides.

• Tác giả: Zhiying Bian, Jie Ding, Qian Liu, Xin Liu, Yuhong Liu, Di Wang, Chuanxiang Zhang, Xin Zhang, Zhiyuan Zhang, Lihao Zhu
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : International journal of biological macromolecules , 2025
• Bộ sưu tập: NCBI
• ID: 733021

Tóm tắt

To establish a polysaccharide-based quality control method for Salvia miltiorrhiza Radix Et Rhizoma (SMR), and to study the cardioprotective activity of Salvia miltiorrhiza polysaccharides (DSP). DSP samples were isolated from 60 different batches of SMR using hot water leaching and their physicochemical properties and structures were analyzed. Multiple DSP fingerprints were established, and zebrafish embryo experiments were designed. The DSP content ranged from 1.68 %-4.06 % as determined by the phenol-sulfuric acid method and high-performance liquid chromatography monosaccharide summation. The molecular weight distribution of DSP was analyzed using molecular weight fingerprints as A: 1.302-2.380 × 10