Hepatic lipid metabolism is altered in Ubiad1

• Tác giả: Knut T Dalen, Simon N Dankel, Christian A Drevon, Johan Fernø, Ryoko Higa, Pratibha S Kolan, Aldons J Lusis, Gunnar Mellgren, Frode A Norheim, Calvin Pan, Shirin Pourteymour, Marcus M Seldin
• Ngôn ngữ: eng
• Ký hiệu phân loại: 959.9042 *Philippines
• Thông tin xuất bản: England : Scientific reports , 2025
• Bộ sưu tập: NCBI
• ID: 733146
• Chủ đề: 1. Hepatic; 2. Lipid; 3. Metabolism

Tóm tắt

UbiA prenyltransferase domain containing 1 (Ubiad1) has the potential to affect cholesterol and phospholipid levels in different cell types. We previously identified Ubiad1 as a candidate gene for regulating subcutaneous fat pad weight in a mouse genome-wide association study. Here we evaluated the relationship between Ubiad1 and obesity-related traits in cohorts of humans and mice, and in Ubiad1