Epidemiological Dynamics in Populations Structured by Neighbourhoods and Households.

• Tác giả: Ben Adams, Abby Barlow, Sarah Penington
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Bulletin of mathematical biology , 2025
• Bộ sưu tập: NCBI
• ID: 733296

Tóm tắt

Epidemiological dynamics are affected by the spatial and demographic structure of the host population. Households and neighbourhoods are known to be important groupings but little is known about the epidemiological interplay between them. In order to explore the implications for infectious disease epidemiology of households with similar demographic structures clustered in space we develop a multi-scale epidemic model consisting of neighbourhoods of households. In our analysis we focus on key parameters which control household size, the importance of transmission within households relative to outside of them, and the degree to which the non-household transmission is localised within neighbourhoods. We construct the household reproduction number