Pre- and post-diagnosis dietary patterns and overall survival in patients with epithelial ovarian cancer: a prospective cohort study.

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Tác giả: Fan Cao, Xi-Yang Chen, Song Gao, Ting-Ting Gong, Dong-Hui Huang, Xiao-Ying Li, Yi-Zi Li, Fang-Hua Liu, Jia-Cheng Liu, Qi-Peng Ma, Ying Qin, Lei Wang, Yi-Fan Wei, Lang Wu, Qi-Jun Wu, Qian Xiao, He-Li Xu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : BMC cancer , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 733324

BACKGROUND: Previous studies have examined the associations between individual foods or nutrients, but few studies have considered dietary patterns associated with ovarian cancer (OC) survival. METHODS: In a prospective cohort study, we examined the association between pre-diagnosis and post-diagnosis overall diet, including changes from pre-diagnosis to post-diagnosis, and overall survival (OS) in 560 patients with OC. Dietary intake was collected using a valid 111-item food frequency questionnaire. Principal component analysis was performed to determine the dietary patterns. Cox proportional hazard regression models were used to assess the hazard ratio (HRs) and 95% confidence interval (CIs). RESULTS: Two dietary patterns were identified: Balanced and nutritious pattern and Energy-dense pattern. The highest tertile of the post-diagnosis Balanced and nutritious pattern scores was related to better OS compared with the lowest tertile (HR = 0.40, 95% CI = 0.17-0.95, P CONCLUSIONS: Greater adherence to the Balanced and nutritious pattern as well as less adherence to the Energy-dense pattern from pre-diagnosis to post-diagnosis were associated with better OC survival.
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