BACKGROUND: In recent years, the Moroccan Ministry of Health and Social Protection has invested considerable resources in implementing electronic health record (EHR) systems to provide citizens with quality healthcare services through efficient structures. However, the rhythm of EHR deployment across the country is very slow, requiring urgent evaluation to remove barriers to successful EHR adoption. OBJECTIVE: This study aims to investigate the critical factors affecting healthcare providers' performance post-EHR implementation in Moroccan public hospitals. METHODS: A cross-sectional study was conducted in three hospitals affiliated with Hassan II University Hospital Center in Fez. Data were collected using a questionnaire survey administered to a sample of 368 healthcare providers from March 2021 to July 2021. Clinician performance was assessed using a proposed research model that integrates the Information System Success Model and the Technology-Organization-Environment framework. The final model was analyzed and tested by using structural equation modeling. Statistical analyses were conducted using SPSS version 25 and Amos version 26. RESULTS: The findings highlighted that the most critical factors influencing clinician performance are clinician satisfaction (β = 0.5, p <
0.002), followed by organization (β = 0.28, p <
0.002), and system quality (β = 0.17, p = 0.01). Additionally, information quality indirectly affects clinician performance (β = 0.19, p <
0.002). However, the environmental factor does not appear to have a significant impact (β = -0.004, p = 0.94). CONCLUSION: This study, performed for the first time in Morocco, identifies key factors for policymakers and healthcare organizations to enhance the successful implementation of EHR systems. Additionally, it serves as a valuable framework for future studies in this area.