OBJECTIVES: To demonstrate the implementation of a digital workflow for the rehabilitation of a terminal dentition patient with complete-arch implant-supported prostheses. CLINICAL CONSIDERATIONS: A virtual patient-oriented workflow can facilitate interdisciplinary treatment planning, improving the synergism between surgical and prosthetic procedures. Digital technologies assisted the acquisition of prosthetic information and optimized dental implant placement, provisional restoration fabrication, and delivery of definitive prostheses. CONCLUSIONS: Digital processing methods enable the integration of cutting-edge technological innovations, with fundamental prosthetic and surgical principles, to build individualized workflows for immediate implant placement and loading, aiming to provide improved patient care in comprehensive rehabilitation. To ensure predictable outcomes, a thorough diagnosis and data collection are needed for selecting the appropriate digital workflow, based on the latest scientific evidence. CLINICAL SIGNIFICANCE: For patients with terminal dentition, clinicians can integrate artificial intelligence (AI) driven applications to form a comprehensive treatment plan. The virtual treatment plan can then be transferred to clinical practice, enabling surgical and prosthetic interventions for complete-arch, immediate implant placement and loading through a digital workflow.