OBJECTIVES: To evaluate the effect of factors on the space between the posterior capsule and IOL. METHODS: A total of 126 patients were included in the study. All patients underwent AS-OCT examinations after surgery. The relationship between the posterior capsule-IOL (PC-IOL) adhesion range and various factors, including IOL type, follow-up period, axial length, and lens thickness, were analyzed. RESULTS: When the follow-up period was shorter than 1 week, the proportion of PC-IOL adhesion range greater than 1/2 in the ZA9003, softec, SN6ATX, and 525 groups was 66.7%, 78.9%, 25%, and 53.8%, respectively. When the follow-up period was longer than 1 month, these proportions increased to 75%, 100%, 40.8%, and 100%, respectively. In the multivariate logistic regression analysis, only the IOL types and follow-up period were statistically significant, while axial length and lens thickness were not statistically significant. CONCLUSION: The follow-up period and IOL types affect the space between the IOL and the posterior capsule, whereas axial length and lens thickness do not. Among the four IOL types studied, the softec IOL has the strongest adhesive power, while the SN6ATX IOL has the weakest.