The present adenomyosis treatment status in Luzhou, China: a small scope observational cross-sectional survey.

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Tác giả: Xinyu Chen, Qiuling Shi, Lingling Xie, Wei Xu, Mengsi Yang, Luxia Yao, Yuan Yuan

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : BMC women's health , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 734422

 OBJECTIVE: To evaluate the current treatment status and management deficiencies of adenomyosis in Luzhou, China. MATERIALS AND METHODS: A small-scale observational cross-sectional study of patients whose imaging suggests adenomyosis from July 2018 to February 2022 at a teaching hospital in Luzhou, China. All participants (1542 patients) completed a questionnaire of 14 items, including basic information, symptoms, treatment options, outcomes, and costs. The patients' treatment options and the hysterectomy rate were evaluated. RESULTS: The treatment options of hormone agents included combined oral contraceptive pills (COCs), gonadotropin-releasing hormone analogues (GnRH-a), levonorgestrel-releasing intrauterine system (LNG-IUS), and dienogest for 2.07, 46.04, 63.49, and 4.67% of patients, respectively. The treatment options under uterus-sparing surgery included adenomyectomy and high-intensity focused ultrasound (HIFU) treatment, presenting in 3.76 and 33.27% of patients, respectively. Finally, 458 (29.70%) patients chose a hysterectomy. The hysterectomy rate between the hormone and uterus-sparing surgery sequential hormone groups (surgery group) was not significantly different (14.8 vs. 12.7%, χ2 = 0.344, P >
  0.05). However, for the focal type and patients with >
  24 months delayed treatment interval, the hysterectomy rate of the hormone group was significantly higher than that of the surgery group (8.5% vs. 1.3%, χ2 = 11.722, P <
  0.01 and 26.7% vs. 18.5%, χ2 = 4.906, P <
  0.05, respectively). CONCLUSIONS: There were treatment delays and treatment selection bias in managing adenomyosis in Luzhou, China. Popular science education and early individualized hormone therapy are needed. Uterine-sparing surgery should be carefully selected.
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