A Man with Primary Hyperchylomicronemia with Triglyceride Levels Exceeding 11,000 mg/dL Was Well Controlled by Pemafibrate Combined with Dietary Therapy.

• Tác giả: Hisatoyo Hiraoka, Yoshito Itoh, Ryuya Iwamoto, Masahiro Koseki, Yuji Matsuzawa, Ryohei Mineo, Takuya Sugiyama, Sachiko Tamba, Hiroyuki Ueda, Yuya Yamada, Koji Yamamoto
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.152 *Anemia
• Thông tin xuất bản: Japan : Internal medicine (Tokyo, Japan) , 2025
• Bộ sưu tập: NCBI
• ID: 735508

Tóm tắt

 A 50-year-old man with a triglyceride (TG) level of 11,397 mg/dL was admitted to our hospital. He consumed a high-fat and high-carbohydrate diet as well as more than 100 g of alcohol per day. He had type 2 diabetes and obesity and had previously suffered from severe acute pancreatitis twice. A genetic analysis revealed compound heterozygous mutations in APOA5 (c.56C>
 G and c.553G>
 T). In addition to low-fat meals and alcohol cessation, administration of pemafibrate lowered his triglyceride levels to <
 150 mg/dL.