STUDY OBJECTIVES: Determine whether preterm-born adolescents and adults have sleep-disordered breathing, as documented by abnormal overnight oximetry. METHODS: This single-center cross-sectional study prospectively enrolled adolescents and adults born moderately to extremely preterm (≤ 32 weeks gestation or <
1,500-g birth weight) or full term to complete a study visit, STOP-Bang questionnaire, and overnight oximetry. Oxygen desaturation index (ODI) was compared in preterm vs term with Poisson regression models. Subgroup analyses in preterm participants evaluated associations of neonatal risk factors with ODI. RESULTS: Ninety-six preterm and 44 term participants completed study procedures. Preterm participants more often reported snoring (25% vs 9%
CONCLUSIONS: Preterm-born adolescents and adults in this study have higher rates of snoring, daytime fatigue, and nocturnal desaturations compared to those term-born. However, the risk of elevated ODI is best attributed to obesity in this cohort and not the history of prematurity. Additionally, a history of a patent ductus arteriosus increased risk for sleep-disordered breathing. CITATION: Sanchez-Solano NJ, Barton GP, Martinez-Fernandez T, Lee M, Goss KN. Sleep-disordered breathing in a multiethnic cohort of preterm adolescents and adults: assessment of neonatal and subsequent risk factors.