Three-Level Nanoparticle Rocket Strategy for Colorectal Cancer Therapeutics in Photothermal Therapy, Inflammation Modulation, and Cuproptosis Induction.

• Tác giả: Hao Chen, Qianyun Chen, Shuai Han, Ling Huang, Zhou Li, Meiyin Lin, Bin Liu, Jianhua Liu, Xi Rao, Wenting Shang, Hongxia Tian, Yingfeng Tu, Xueer Xia, Yue Zheng, Yuting Zhu
• Ngôn ngữ: eng
• Thông tin xuất bản: Germany : Advanced healthcare materials , 2025
• Bộ sưu tập: NCBI
• ID: 736941

Tóm tắt

Disturbances in intracellular copper (Cu) homeostasis can trigger cuproptosis, a new form of cell death, which, when combined with photothermal therapy (PTT), offers a promising solution to the persistent challenges in colorectal cancer (CRC) treatment. In this study, a "three-level nanoparticle rocket" strategy is developed by engineering Cu