The SET29 and SET7 proteins of Leishmania donovani exercise non-redundant convergent as well as collaborative functions in moderating the parasite's response to oxidative stress.

• Tác giả: G Aneeshkumar Arimbasseri, Somdeb Chattopadhyay, Vishal Dashora, Yogita Kapoor, Jyoti Pal, Swati Saha, Varshni Sharma, Biplab Singha
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The Journal of biological chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 737266

Tóm tắt

SET proteins are lysine methyltransferases. In investigating Leishmania donovani SET29, we found depletion of LdSET29 by two-thirds did not affect promastigote growth, nor alter the parasite's response to UV-induced or HU-induced stress, but made it more tolerant to H