The estimation of peripheral dose (PD) is vital in cancer patients with long life expectancy. Assessment of PD to radiosensitive organs is important to determine the possible risk of late effects. An attempt has been made to assess the peripheral dose using optically stimulated luminescence dosimeter (OSLD) with megavoltage photon beams as a function of field size, depth, energy, and distance from the field edge. The PD measurements were carried out at 13 locations starting from 1.5 cm to 20.8 cm from radiation field edge for three different field sizes at three different depths with 6 and 18 MV photon beams. In addition, the measurements were carried out to analyze the response in PD due to the presence of wedge. The %PD decreases gradually with an increase in distance from the radiation field edge. The %PD at surface for 10 × 10cm