SCN5A missense variants and their contribution to deaths in Sudden Unexplained Nocturnal Death Syndrome (SUNDS).

• Tác giả: Vichaya Auvichayapat, Saknan Bongsebandhu-Phubhakdi, Aummarin Chaloemthanetphong, Kiattawee Choowongkomon, Ashfaque Ahmed Kanhar, Irin Lertparinyaphorn, Napapat Natthasumon, Hasnee Noh, Tikumphorn Sathirapatya, Poonyapat Sukawutthiya, Nattachai Thangsiriskul, Pagparpat Varrathyarom, Kornkiat Vongpaisarnsin, Wikanda Worrapitirungsi
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Forensic science international. Genetics , 2025
• Bộ sưu tập: NCBI
• ID: 738470

Tóm tắt

Sudden Unexplained Nocturnal Death Syndrome (SUNDS), locally known as Lai-tai in Thailand, leads to sudden death during sleep in otherwise healthy young males. Cardiac arrhythmias, including Brugada syndrome (BrS) and Long QT syndrome (LQTS), are often implicated, with mutations in the SCN5A gene, encoding the Na