Particle size transfer of antibiotic resistance genes in typical processes of municipal wastewater treatment plant.

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Tác giả: Yufeng Chai, Min Chen, Mengmeng Liu, Peihong Shen, Qihe Tang, Yuansong Wei, Xiaojie Yan, Min Yang, Junya Zhang

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : Bioresource technology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 738721

 Occurrence and transfer of antibiotic resistance genes (ARGs) was investigated concerning sludge particle size in a typical wastewater treatment plant, and the roles of vertical (VGT) and horizontal gene transfer (HGT) in the spread of ARGs were explored. Results showed that although membrane bioreactor (MBR) effectively reduced the relative abundance of ARGs in the water phase, it concurrently enriched ARGs in MBR sludge, particularly for the largest-size particles (>
 150 μm). A decreasing trend in the relative abundance of ARGs was observed along with the decrease of sludge particle size, and larger-size particle sludge (>
 106 μm) formed a relatively stable composition of ARGs, while ARGs on smaller-size particle sludge (6.5-106 μm) fluctuate rapidly. Particle size does not affect the abundance distribution patterns or assembly mechanisms of ARGs as deterministic processes. The smallest-size particles were the primary attachment site for bacterial pathogens with highest diversity. Larger-size particle sludge (>
 106 μm) showed higher frequency of HGT, with Proteobacteria as the dominant hosts for this process.
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