Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.

• Tác giả: Alejandro Alagón, Melisa Bénard-Valle, Miguel Borja, Julián Fernández, Leonardo Fernández-Badillo, Uri O García-Vázquez, Bruno Lomonte, Nallely Morales-Capellán, Edgar Neri-Castro, Alejandro Olvera-Rodríguez, Gibrán Rodríguez-Barrera, Bruno Rodríguez-López, Audrey Michelle Rodríguez-Solís, Anthony Saviola, Fernando Zamudio, Vanessa Zarzosa
• Ngôn ngữ: eng
• Ký hiệu phân loại: 355.242 Metals
• Thông tin xuất bản: Netherlands : Journal of proteomics , 2025
• Bộ sưu tập: NCBI
• ID: 739438
• Chủ đề: 1. Integrative; 2. Transcriptomic; 3. Proteomic

Tóm tắt

Species of the genus Micrurus belong to the family Elapidae and possess venoms of significant clinical importance. This study presents an analysis of the venom composition of Micrurus ephippifer, employing transcriptomic and proteomic methodologies. A total of 2885 venom gland transcripts were assembled, of which 42 were identified as toxins. Transcripts for three-finger toxins (3FTx) were the most abundant (80.7 %), followed by PLA