Genetic mutation in HSF4 is associated with retinal degeneration in mice.

• Tác giả: Yanzhong Hu, Xiaolin Jia, MingJun Jiang, Youfei Lang, Yujie Li, Baixue Liu, Xuyan Peng, Mengjiao Xue
• Ngôn ngữ: eng
• Ký hiệu phân loại: 523.88 Kinds of stars characteristic of stages of stellar evolution
• Thông tin xuất bản: England : Experimental eye research , 2025
• Bộ sưu tập: NCBI
• ID: 739473

Tóm tắt

Genetic mutations in Hsf4 cause developmental defect of lens at postnatal age. However, the regulatory effect of Hsf4 mutations on retinal homeostasis have not been elucidated. Here we found that HSF4 expresses in retinal and its expression level decrease with age increase. Using Hsf4