Formoterol alters chemokine expression and ameliorates pain behaviors after moderate spinal cord injury in female mice.

• Tác giả: Kiara J Bachtle, Kristian Doyle, Jennifer B Frye, Tally Marie Largent-Milnes, Sanna H Loppi, Ingrid L Peterson, Rick G Schnellmann, Natalie E Scholpa, Austin D Thompson
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The Journal of pharmacology and experimental therapeutics , 2025
• Bộ sưu tập: NCBI
• ID: 739779

Tóm tắt

Secondary spinal cord injury (SCI) is characterized by increased cytokines and chemokines at the site of injury that have been associated with the development of neuropathic pain. Nearly 80% of SCI patients report suffering from chronic pain, which is poorly managed with available analgesics. While treatment with the US Food and Drug Administration-approved β