An Atypical Kappa-Class Chaperone-Usher Fimbriae of a Human Enterotoxigenic Escherichia coli Strain Shows Multi-Host Adherence and Distinct Phylogenetic Feature.

• Tác giả: Hisashi Aso, Erika Ban-Furukawa, Hiharu Inoue, Miyoko Inoue, Eriko Kage-Nakadai, Yoshikazu Nishikawa, Yuko Omori, Taro Tachibana, Yoshihiko Tanimoto, Takayuki Wada, Yoshihiro Yamaguchi, Weiping Zhang, Dongming Zheng
• Ngôn ngữ: eng
• Thông tin xuất bản: Australia : Microbiology and immunology , 2025
• Bộ sưu tập: NCBI
• ID: 739952

Tóm tắt

The pathogenesis of enterotoxigenic Escherichia coli (ETEC) involves the colonization of hosts by colonization factors (CFs) and the secretion of enterotoxins. CFs, especially chaperone-usher fimbriae, mediate bacterial adhesion to host cells, with extensive genetic diversity observed among isolates. One ETEC strain, O169YN10, possessed a unique plasmid (pEntYN10) encoding three CFs, CS6, and two novel homologs of CS8 and F4 (CS6