OBJECTIVE: Aim: To establish taxonomic composition, population level and microecological indicators of the "macroorganism-microbiota" ecosystem by determining the expression levels of individual pathogenicity factors of microorganisms isolated from the skin areas of patients with paratraumatic eczema developed as a result of combat injuries. PATIENTS AND METHODS: Materials and Methods: Studied microbiologically eczematous lesions content in 54 military men to determine the qualitative and quantitative composition of microbiocenosis to analyze the taxonomic composition, population-species level, microecological indicators and expression levels of individual pathogenicity factors. RESULTS: Results: The results indicate that most eczematized areas are contaminated with S.aureus (48.1% ) with the highest level of quantitative dominance. The rate of quantitative dominance of other strains is significantly lower: S.epidermidis - 2.56 times, S.haemolyticus - 4.56 times, S.pyogenes - 5.86 times, E.faecalis and K.pneumoniae - 20.56 times. When determining the sensitivity of S. aureus clinical strains to antibacterial drugs, we established high levels of sensitivity to mupirocin, fusidic acid, and oxazolidinones - 95.1%, 90.2%, and 87.8%, respectively. Moreover, S. aureus dominated among the strains with a high ability to form biofilms - 68.2%, with an average ability - S epidermidis, 28.8%. CONCLUSION: Conclusions: S.aureus is the leading pathogen in the infectious-allergic process with paratraumatic eczema according to the constancy index of each taxon, frequency of manifestation, Margalef's species richness index, Whittaker's species diversity, the value of Simpson's and Berger-Parter's species dominance indices, as well as the population level of each taxon, the coefficient of quantitative dominance and the coefficient of significance. We should consider this fact when prescribing therapy.