Lactiplantibacillus plantarum JM113 alleviates mitochondrial dysfunction induced by deoxynivalenol in the jejunum of broiler chickens.

• Tác giả: Qihang Hou, Saisai Liang, Xinying Lv, Zhouzheng Ren, Lvhui Sun, Haonan Tong, Xiaojun Yang, Xin Yang, Haotian Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.453 Tin
• Thông tin xuất bản: England : Poultry science , 2025
• Bộ sưu tập: NCBI
• ID: 740178
• Chủ đề: 1. Lactiplantibacillus; 2. Plantarum; 3. Jm113

Tóm tắt

Mitochondria are primary targets of deoxynivalenol (DON), which play a pivotal role in maintaining intestinal health. It has been suggested that Lactiplantibacillus plantarum JM113 (L. plantarum JM113) exhibits protective effects against the enterotoxicity of DON in broilers. However, the changes in mitochondrial homeostasis during this process remain unclear. A total of 144 one-day-old Arbor Acres broilers were randomly assigned to 3 groups, including the CON group (fed a basal diet and gavaged with 0.5 mL PBS), the DON group (supplemented with 5 mg/kg DON based on the CON group) and the DJ group (fed a basal diet challenged with 5 mg/kg DON and gavaged with 1 × 10