Identification of molecular biomarkers in human serum for chronic kidney disease using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy.

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Tác giả: Rajda Chaichit, Patutong Chatchawal, Doosadee Hormdee, Poramaporn Klanrit, Cholatip Pongskul, Kamonchanok Tangwanichgapong, Molin Wongwattanakul

Ngôn ngữ: eng

Ký hiệu phân loại: 230.0071 Christianity Christian theology

Thông tin xuất bản: England : Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 740267

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Chronic kidney disease (CKD) and its progression to end-stage renal disease (ESRD) represent significant global health challenges, contributing to increased morbidity and mortality. Despite the potential diagnostic value of ATR-FTIR spectroscopic analysis of serum in CKD, research in this area remains limited. This study addressed this gap by aiming to explore the spectral profiles of sera obtained from hemodialysis patients and healthy controls. We investigated serum spectral profiles from 21 hemodialysis patients and 21 age/sex-matched controls using ATR-FTIR spectroscopy in the mid-infrared region (4000-400 cm

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