This empirical and qualitative study focuses on COVID-19 crisis management in a French hospital, analyzing it from the perspective of organizational resilience to understand its evolution over time. The study identifies adaptation factors during pandemic management, supported by success factors, and it also identifies difficulty factors associated with resilience. These factors are analyzed at the different waves of the pandemic to understand the evolution of organizational resilience across various crisis management temporalities. The results highlight how certain factors initially considered as resilience capabilities, evolve to become vulnerability factors of the sociotechnical system, in particular due to their impacts on healthcare personnel.