A strategy for electrochemical biosensing based on dendritic HCR amplification for detection of RNA m5C and m6A methylation.

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Lichao Fang, Yue Hu, Hui Huang, Chenghong Li, Lulu Li, Mimi Li, Huamin Liu, Yi Liu, Kexing Peng, Lina Wang, Xiaolong Wang, Shuang Xu, Junsong Zheng

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Netherlands : Analytica chimica acta , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 740821

Sensitive and efficient detection of RNA methylation sites is considered an integral part of epigenetic assessment. Contrary to previous studies on the detection of RNA m5C or m6A methylation alone, this study innovatively designed a biosensor capable of detecting RNA m5C or m6A methylation at the same time. Substances with specific electrochemical reactions such as ferrocene (FC) or methylene blue (MB) were modified onto the hairpin probe. When the hairpin probe was activated under specific conditions, it triggered a dendritic nonlinear hybridization chain reaction (HCR), which resulted in signal amplification. Gold (Au) and iron tetraoxide (Fe
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH