Antigen-specific immunotherapy of multiple sclerosis and other autoimmune diseases.

• Tác giả: David C Wraith
• Ngôn ngữ: eng
• Ký hiệu phân loại: 028.53 Reading and use of other information media by specific age groups
• Thông tin xuất bản: United States : Seminars in arthritis and rheumatism , 2025
• Bộ sưu tập: NCBI
• ID: 740987

Tóm tắt

Current therapies for autoimmune diseases do not address the underlying cause of disease, the failure of immune tolerance to self. The non-specific therapies currently used to treat autoimmune diseases increase the risk of infections and cancers. Antigen-specific therapies target pathogenic autoreactive lymphocytes while preserving protective immune responses. This short synthesis will review our laboratory's work on the design and development of antigen-specific immunotherapies for multiple sclerosis and other autoimmune diseases.