Trunk muscle differentiation-a lesson from the Chinese fire-bellied newt (Hypselotriton orientalis).

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Tác giả: Marta Julianna Brania, Małgorzata Daczewska, Magda Dubińska-Magiera, Katarzyna Haczkiewicz-Leśniak, Krzysztof Kolenda, Marta Migocka-Patrzałek

Ngôn ngữ: eng

Ký hiệu phân loại: 133.5266 Astrology

Thông tin xuất bản: Austria : Protoplasma , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 741033

Extant amphibians are divided into three distinct lineages: Gymnophiona, Urodela, and Anura. Owing to their diversity, they are widely used in research concerning, among others, tissue regeneration. Here, we describe larval myotomal myogenesis in the Chinese fire-bellied newt, Hypselotriton orientalis. Morphological, ultrastructural, cytochemical, and immunohistochemical analyses showed that trunk muscles grow through hypertrophy and hyperplasia mediated by the expression of typical myogenic factors, such as Pax7, from muscle progenitor cells. Our findings also suggest a third alternative mechanism for muscle growth involving the muscle splitting or fragmentation of preexisting larval myotubes.
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