New abietane-type diterpenoids from roots of Euonymus hamiltonianus and their cytotoxicity in human cancer cell.

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Tác giả: Young-Won Chin, Jungmoo Huh, Jae Hyun Lee, Won Keun Oh, Chan-Woong Park, Eun Jin Park, Tae-Jin Yang

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Japan : Journal of natural medicines , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 741141

Two new abietane-type diterpenoids, 6β-(3-furoyloxy)ferruginol (1) and 6-chloro-6,7-dehydroferruginol (2), were isolated from the roots of Euonymus hamiltonianus along with five known diterpenoids (3-7). Their structures were characterized using various spectroscopic analysis including HRMS, 1D and 2D NMR, and ECD analysis. All isolated compounds (1-7) were evaluated for their cytotoxic activity against human colon cancer cell line, HCT116, and it was found to exhibit moderate cytotoxic activity with IC
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