Corrosion remains a pivotal issue that significantly reduces the lifespan of metallic materials. Laser cladding technology, renowned for its exceptional effectiveness in bolstering the surface corrosion resistance of metal materials, has garnered considerable attention and interest. We propose utilizing laser cladding technology to apply a high-entropy alloy coating onto 45# steel to enhance the properties of the substrate. After undergoing an electrochemical test, the surface of coating was covered with a smooth film. The coating demonstrated exceptional corrosion resistance and adhesion qualities. By implementing this strategy, the corrosion resistance of 45# steel members can be significantly enhanced.