An optical ratiometric approach using enantiopure luminescent metal complexes indicates changes in the average quadruplex DNA content as primary cells undergo multiple divisions.

• Tác giả: Simon Fairbanks, Caroline Glover, Nicola H Green, F Richard Keene, Craig C Robertson, Jim A Thomas
• Ngôn ngữ: eng
• Ký hiệu phân loại: 004.678 Internet (World Wide Web)
• Thông tin xuất bản: England : Dalton transactions (Cambridge, England : 2003) , 2025
• Bộ sưu tập: NCBI
• ID: 741941

Tóm tắt

The three stereoisomers of a previously reported dinuclear ruthenium(II) complex have been quantitatively separated using cation-exchange chromatography and the individual crystal structures of the racemic pair are reported. Cell-based studies on the three stereoisomers disclosed differences in the rate of uptake of the two chiral forms of the