Specific Interaction between a Fluoroquinolone Derivative, KG022, and RNAs with a Single Bulge.

• Tác giả: Rika Ichijo, Gota Kawai
• Ngôn ngữ: eng
• Ký hiệu phân loại: 025.17 Administration of collections of special materials
• Thông tin xuất bản: United States : Biochemistry , 2025
• Bộ sưu tập: NCBI
• ID: 742218

Tóm tắt

Small compounds targeting RNAs are recognized as a promising modality in drug discovery. We have found that a fluoroquinolone derivative, KG022, binds to RNAs with single-bulged residues. It has been demonstrated by