Photocatalyzed Three-Component Difluoroalkyl-Halogenation of Electron-Deficient Alkenes via a Halogen α-Nucleophilic Addition.

• Tác giả: Di Chao, Qingfeng Liu, Tongxin Liu, Xiaoxiao Liu, Yingchao Ma, Guisheng Zhang, Xingjie Zhang, Zhiguo Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 539.7217 Atomic and nuclear physics
• Thông tin xuất bản: Germany : Chemistry (Weinheim an der Bergstrasse, Germany) , 2025
• Bộ sưu tập: NCBI
• ID: 742278

Tóm tắt

Here, we disclose a halogen α-nucleophilic addition via photocatalytic oxidation of the in-situ generated α-carbonyl radical of amides or esters to corresponding α-carbonyl cation. The α-carbon radical is generated by the β-addition of difluoroalkyl radical, formed by the photocatalytic reduction of BrCF